| Comment |
The rearranged qualifier should not be used to annotate chromosome rearrangements that are not involved in an adaptive immune response; germline and rearranged qualifiers cannot be used in the same source feature; germline and rearranged qualifiers should only be used for molecules that can undergo somatic rearrangements as part of an adaptive immune response; these are the T-cell receptor (TCR) and immunoglobulin loci in the jawed vertebrates, and the unrelated variable lymphocyte receptor (VLR) locus in the jawless fish (lampreys and hagfish); germline and rearranged qualifiers should not be used outside of the Craniata (taxid=89593) |